Creamy Southwest Chicken Alfredo – Easy 30 Minute Dinner

If you love classic Chicken Alfredo but crave a little extra kick, this Southwest Chicken Alfredo is for you! Creamy, cheesy, and full of bold flavor, this easy pasta recipe is perfect for busy weeknights. Plus, it’s ready in just 30 minutes!

Ingredients:

  • 1 lb. Chicken Breasts, cut into 1” strips
  • 1/2 lb. Penne Pasta
  • 1 (15oz.) can Diced Tomatoes
  • 1 cup Heavy Cream
  • 1 1/2 cups Cheddar Cheese, shredded
  • 1 cup Onion, chopped
  • 4 Garlic Cloves, minced
  • 1 tablespoon Honey
  • 1 tablespoon Olive Oil
  • 1 tablespoon Butter
  • 2 tablespoons Cilantro, chopped

Southwest Seasoning:

  • 1 1/2 teaspoon Chili Powder
  • 1/2 teaspoon Cumin
  • 1/2 teaspoon Oregano
  • 1 teaspoon Paprika
  • 1/4 teaspoon Black Pepper
  • 1/2 teaspoon Salt
  • 1/8 teaspoon Cayenne

Instructions:

1. In a small bowl, mix the southwest seasoning blend together

2. Add cut chicken to a large bowl and drizzle in honey and the seasoning blend. Toss to combine

3. Bring a large pot of salted water to boil and cook pasta according to package directions. Drain and set aside.

4. Heat olive oil in a large skillet over medium-high heat. Add chicken and cook until golden and fully cooked (about 6-8 minutes). Transfer to a plate

5. In the same skillet, add onion and butter. Cook for a few minutes until tender. Add garlic and cook another minute. Add diced tomatoes and bring to a low simmer.

6. Slowly pour in heavy cream while stirring until fully incorporated. Bring to a nice simmer. Add chicken back to the skillet. Sprinkle in cheddar cheese and stir to combine. Add penne pasta to the sauce and toss to combine. Remove pasta from heat and let sit a few minutes.

7. Top with fresh cilantro and extra cheese if desired. Serve immediately!

Tips & Variations:

Swap penne for fettuccine for a classic Alfredo feel. Add a pinch of cayenne or red pepper flakes for extra heat. Want more veggies? Add sautéed bell peppers or corn for a true Southwest vibe.

Cookware I Used:

I made this using my favorite nonstick pots and pans set—it’s a game changer in the kitchen!

👉 Check it out here (affiliate link)

If you’re looking for a dinner that’s packed with flavor, easy to make, and family-approved, this Creamy Southwest Chicken Alfredo is a must-try! It’s the perfect way to bring a little spice to your weeknight meal rotation without spending hours in the kitchen.

🎥 Watch the full recipe video here: https://youtube.com/shorts/I1lqrveSLow?si=xC0GFxJVWcnJaVej

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Author: Katie

Hi, I’m Katie —full-time working mom, part-time short-order cook, and the heart behind From Work to Table. After a long day at work, I come home to the real challenge: making a meal that brings my family together, satisfies at least one extremely picky eater, and doesn’t take an hour (or all my energy) to pull off. This blog is my place to share the recipes, shortcuts, and survival strategies I’ve learned along the way—meals that fit into the chaos of real life without sacrificing taste, nutrition, or sanity. Whether you’re a fellow working parent, a tired caregiver, or just someone looking for a way to get dinner on the table a little faster and with a little less stress, welcome. You’re not alone—and dinner doesn’t have to be perfect to be meaningful. Let’s find what works, one meal (and one picky bite) at a time.

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